New model proposed to modify brain cancer risk

New model proposed to modify brain cancer risk

Posted 12 January, 2022 at 08:55

Author Jessica McClory on behalf of In Sues Name


It has been reported previously that children with asthma seem to be less likely to develop brain tumours than others. A reduction in the incidence of optic gliomas was also seen in children with Neurofibromatosis type 1 (NF1) brain cancer predisposition who also had asthma. Researchers have proposed a new model in which brain cancer risk is modified by alterations in the function of circulating T cells. In this new mouse study, researchers discovered that asthma causes the T cells to behave in a way that induces lung inflammation but prevents the growth of brain tumours.

This paper on the reduction of glioma formation by T cell decorin-mediated inhibition of microglia is published in Nature Communications.

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In Sue’s Name was founded in 2014 by David Taylor in memory of his beloved daughter Sue Blasotta, who died in 2011 of brain tumours. Sue was devoted to her husband Joe and their children Sasha and Daniel. She adored her career, first in recruitment with Reed Employment and then caring for ch...

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